CBR is the Center for Biomembrane Research at Stockholm University. CBR is funded by a strategic initiative to advance Swedish research on membranes, membrane proteins, and biomembrane-related functionality. CBR hosts 19 internationally competitive research labs working in areas ranging from bioinformatics and structure modelling to membrane protein biogenesis, oligomerization and expression/purification. SBC is the leading national center in bioinformatics in Sweden. It was co-founded by Arne Elofsson in 1999. It hosts 6 groups and in totals more than 20 researchers, 10 PhD students and 1 postdoc. The research focuses on the development of algorithms in protein structure prediction, orthology analysis, membrane proteins and evolutionary analysis.

High-throughput capability

A dedicated computing cluster of approximately 1000 CPU-cores will be installed in Stockholm during 2007 in addition to the existing cluster of 350 CPUs.

Tasks allocated

Development of algorithms to predict the risk of obtaining Multiple Sclerosis and Rheumatoid Arthritis provided HLA typing. (T3.3).

 

Previous experience

Arne Elofsson has developed a number of frequently used algorithms in different areas of bioinformatics during the last decade. His work has focused on protein structure predictions, but he has also experience in development of algorithms for MHC binding and other machine learning tasks. He has also pioneered the analysis of evolution of multi-domain proteins.

The main role of Stockholm University is the design of the genomic microarrays of HLA typing. SU will work on software development of the database and the Desktop Diagnostic System.

Website: www.su.se